HCN2 modulator-4
HCN2 modulator-4 is a HCN2 ion channel inhibitor. HCN2 modulator-4 inhibits HCN2 ion channel activity. HCN2 modulator-4 can be used for the research of pain, inflammatory pain, neuropathic pain, tinnitus, central nervous system disorders, psychiatric disorders, mood disorders.
For research use only. We do not sell to patients.
- CAS No.: 3080809-03-3
- Formula: C23H21FN4O5
- Molecular Weight:452.44
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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KCNQ2 |
HCN2 modulator-4 (R-configuration 39; 5 minutes) potently inhibits human HCN2 channels with an IC50 of 10 nM, with reduced activity against human HCN1 and HCN4 channels[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3080809-03-3
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Molecular Weight 452.44
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Formula C23H21FN4O5
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SMILES
O=C(C1=C(OC=C1)C)NC2=NN(C[C@@H](C)OC)C3=NC=C(C4=CC(F)=C(OCO5)C5=C4)C=C23
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)