1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. Hydroxypyruvic acid lithium hydrate

Hydroxypyruvic acid lithium hydrate (Synonyms: β-Hydroxypyruvic acid lithium hydrate; 3-Hydroxypyruvic acid lithium hydrate)

Cat. No.: HY-113013A
Handling Instructions

Hydroxypyruvic acid lithium hydrate (β-Hydroxypyruvic acid lithium hydrate) is an intermediate in the metabolism of glycine, serine and threonine. Hydroxypyruvic acid lithium hydrate is a substrate for serine-pyruvate aminotransferase and glyoxylate reductase/hydroxypyruvate reductase. Hydroxypyruvic acid lithium hydrate is involved in the metabolic disorder which is the dimethylglycine dehydrogenase deficiency pathway.

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Hydroxypyruvic acid lithium hydrate Chemical Structure

Hydroxypyruvic acid lithium hydrate Chemical Structure

CAS No. : 209728-15-4

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Description

Hydroxypyruvic acid lithium hydrate (β-Hydroxypyruvic acid lithium hydrate) is an intermediate in the metabolism of glycine, serine and threonine. Hydroxypyruvic acid lithium hydrate is a substrate for serine-pyruvate aminotransferase and glyoxylate reductase/hydroxypyruvate reductase. Hydroxypyruvic acid lithium hydrate is involved in the metabolic disorder which is the dimethylglycine dehydrogenase deficiency pathway.

IC50 & Target

IC50: intermediate; substrate

In Vivo

Hydroxypyruvic acid (lithium hydrate) (intravenous injection; 100 mg/ml; slowly over 10 min) increases the 5-h urinary oxalate and glycolate excretion to 0.68% (6.56 μmol) and 0.53% (5.10 μmol) in control rats, in addition, it increases to 2.43% (23.36 μmol) and 0.79% (7.59 μmol) of the dose in the vitamin-B6-deficient rats[1].

Molecular Weight

128.01

Formula

C₃H₅LiO₅

CAS No.

209728-15-4

SMILES

O=C(O[Li])C(CO)=O.[H]O[H]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

Hydroxypyruvic acid lithiumβ-Hydroxypyruvic acid lithium3-Hydroxypyruvic acid lithiumEndogenous MetaboliteSubstrateUrinaryoxalateendogenousmetabolicdiorderdimethylglycinedehydrogenasedeficiencyglycineserinethreonineInhibitorinhibitorinhibit

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Hydroxypyruvic acid lithium hydrate
Cat. No.:
HY-113013A
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