2. Others
  3. Drug Intermediate
  4. Ibrutinib impurity 5

Ibrutinib impurity 5  (Synonyms: (S)-Ibrutinib)

Cat. No.: HY-Z2289 Purity: 98.81%
COA
SDS
Handling Instructions Technical Support

Ibrutinib Impurity 5 ((S)-Ibrutinib) is an impurity of Ibrutinib (HY-10997).

For research use only. We do not sell to patients.

Ibrutinib impurity 5

Ibrutinib impurity 5 Chemical Structure

CAS No. : 936563-97-2

Size Price Stock Quantity
10 mg In-stock
25 mg In-stock
50 mg In-stock
100 mg In-stock
200 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Other Forms of Ibrutinib impurity 5:

Ibrutinib impurity 5 Related Antibodies

Top Publications Citing Use of Products

  • Biological Activity

  • Purity & Documentation

  • Customer Review

Description

Ibrutinib Impurity 5 ((S)-Ibrutinib) is an impurity of Ibrutinib (HY-10997).

Cellular Effect
Cell Line Type Value Description References
HEK-293T IC50
2241 nM
Compound: Ibrutinib
Antiproliferative activity against human HEK293T cells assessed as reduction in cell viability incubated for 72 hrs by celltiter-glo assay
Antiproliferative activity against human HEK293T cells assessed as reduction in cell viability incubated for 72 hrs by celltiter-glo assay
[PMID: 34391034]
MOLM-13 IC50
3953 nM
Compound: Ibrutinib
Antiproliferative activity against human MOLM-13 cells assessed as reduction in cell viability incubated for 72 hrs by celltiter-glo assay
Antiproliferative activity against human MOLM-13 cells assessed as reduction in cell viability incubated for 72 hrs by celltiter-glo assay
[PMID: 34391034]
Ramos IC50
11451 nM
Compound: Ibrutinib
Antiproliferative activity against human Ramos cells assessed as reduction in cell viability incubated for 72 hrs by celltiter-glo assay
Antiproliferative activity against human Ramos cells assessed as reduction in cell viability incubated for 72 hrs by celltiter-glo assay
[PMID: 34391034]
TMD8 IC50
1.5 nM
Compound: Ibrutinib
Antiproliferative activity against human TMD8 cells assessed as reduction in cell viability incubated for 72 hrs by celltiter-glo assay
Antiproliferative activity against human TMD8 cells assessed as reduction in cell viability incubated for 72 hrs by celltiter-glo assay
[PMID: 34391034]
Molecular Weight

440.50

Formula

C25H24N6O2
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

C=CC(N1C[C@@H](N2N=C(C3=CC=C(OC4=CC=CC=C4)C=C3)C5=C(N)N=CN=C52)CCC1)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Purity & Documentation

Purity: 99.98%

SDS (393 KB)

COA (257 KB) HNMR (128 KB) RP-HPLC (94 KB) LCMS (266 KB)

Handling Instructions (2659 KB)
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

Ibrutinib impurity 5 Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Ibrutinib impurity 5936563-97-2(S)-IbrutinibIbrutinib impurity5Ibrutinib impurity-5Drug IntermediateDrug IintermediateInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Requested Quantity *

Applicant Name *

 

Salutation

Email Address *

 

Phone Number *

Department

 

Organization Name *

City

State

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Ibrutinib impurity 5
Cat. No.:
HY-Z2289
Quantity:
MCE Japan Authorized Agent:

Customer Review

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Email Address *

Phone Number

 

Department *

Organization Name *

 

Country or Region *

Remarks

SAFETY DATA SHEET (SDS)

English - EN (393 KB) Français - FR (393 KB) Deutsch - DE (393 KB) Norwegian - NO (393 KB) Español - ES (393 KB) Swedish - SV (393 KB) Italian - IT (393 KB) Korean - KR (393 KB) Portuguese - PT (393 KB)

Request for HNMR Report

We have received your request and will respond to you as soon as possible.