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Cat. No.: HY-126475

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KSK213

KSK213 is a 1,2,3-triazole-based Chlamydia infectivity inhibitor with high potency (EC₅₀ ≤ 20 nM) against Chlamydia infectivity.

For research use only. We do not sell to patients.

CAS No.: 1876429-73-0
Formula: C₂₈H₂₅N₃O₂S
Molecular Weight:467.58

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

KSK213 Chemical Structure

CAS No.: 1876429-73-0

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

KSK213 is a 1,2,3-triazole-based Chlamydia infectivity inhibitor with high potency (EC₅₀ ≤ 20 nM) against Chlamydia infectivity.

Cellular Effect

Cell Line	Type	Value	Description	References
HeLa	EC₅₀	58 nM Compound: 21a	Antimicrobial activity against Chlamydia trachomatis serovar D infected in human HeLa cells assessed as decrease in relative inclusion forming units measured 44 to 48 hrs post infection by DAPI staining-based assay Antimicrobial activity against Chlamydia trachomatis serovar D infected in human HeLa cells assessed as decrease in relative inclusion forming units measured 44 to 48 hrs post infection by DAPI staining-based assay	[PMID: 26849778]
HeLa	EC₅₀	59 nM Compound: 21a	Antimicrobial activity against Chlamydia trachomatis serovar LGV-L2 infected in human HeLa cells assessed as decrease in relative inclusion forming units measured 44 to 48 hrs post infection by DAPI staining-based assay Antimicrobial activity against Chlamydia trachomatis serovar LGV-L2 infected in human HeLa cells assessed as decrease in relative inclusion forming units measured 44 to 48 hrs post infection by DAPI staining-based assay	[PMID: 26849778]

Chemical Information

CAS No. 1876429-73-0
Molecular Weight 467.58
Formula C₂₈H₂₅N₃O₂S
SMILES

O=C(C1CSC2=C(C3CC3)C(CC4=C5C=CC=CC5=CC=C4)=C(N)C(N21)=O)NC6=CC=CC=C6
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Thiazolino 2-Pyridone Amide Isosteres As Inhibitors of Chlamydia trachomatis Infectivity

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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