SERTAD2 - SERTA domain containing 2 Gene

Also Known as Sei-2; TRIPBR2; TRIP-Br2

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 9792

About SERTAD2

Cytogenetic location: 2p14 Genomic coordinates (GRCh38): 2:64,631,621-64,653,913 (from NCBI)

This gene has 3 transcripts (splice variants), 186 orthologues and 1 paralogue. Ubiquitous expression in bone marrow (RPKM 29.6), esophagus (RPKM 11.9) and 24 other tissues.

Summary

Predicted to enable transcription coactivator activity. Acts upstream of or within negative regulation of cell growth. Located in cytosol and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

SERTAD2 Products (1)

mRNA Protein Name
NM_014755.3 NP_055570.1 SERTA domain-containing protein 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
Biological Process GO Annotation Evidence References Source
acts upstream of or within negative regulation of cell growth IDA
IDA: Inferred from direct assay
16098148 GOA
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
16098148 GOA
located in nucleus IDA
IDA: Inferred from direct assay
16098148 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

SERTAD2 Protein Structure

SERTA

SERTA: SERTA motif (40 - 77)

  • 0
  • 100
  • 200
  • 300
  • 314 a.a.
Protein Preferred Names Protein Names

SERTA domain-containing protein 2

  • transcriptional regulator interacting with the PHD-bromodomain 2

SERTAD2 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
SERTAD2 Q14140 ZNF524 Homo sapiens Q96C55
Validated Y2H
32296183
Intra
SERTAD2 Q14140 IGFN1 Homo sapiens Q86VF2-5
Validated Y2H
32296183
Intra
SERTAD2 Q14140 CTNNA3 Homo sapiens Q9UI47-2
Validated Y2H
32296183
Intra
SERTAD2 Q14140 HELLS Homo sapiens Q9NRZ9-6
Validated Y2H
32296183
Intra
SERTAD2 Q14140 STRA8 Homo sapiens Q7Z7C7
Validated Y2H
32296183
Intra
SERTAD2 Q14140 ESPNL Homo sapiens Q6ZVH7
Validated Y2H
32296183
Intra
SERTAD2 Q14140 PARVG Homo sapiens Q9HBI0
Validated Y2H
32296183
Intra
SERTAD2 Q14140 KAT5 Homo sapiens Q92993
Validated Y2H
32296183
Intra
SERTAD2 Q14140 ZNF581 Homo sapiens Q9P0T4
Validated Y2H
32296183
Intra
SERTAD2 Q14140 PIK3R3 Homo sapiens Q92569
Validated Y2H
32296183
Intra
SERTAD2 Q14140 AIRIM Homo sapiens Q9NX04
Validated Y2H
32296183
Intra
SERTAD2 Q14140 TNS2 Homo sapiens Q63HR2
Validated Y2H
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12732 SERTAD2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus SERTAD2 MGD MGI:1931026
Felis catus SERTAD2 VGNC VGNC:82426
Macaca mulatta SERTAD2 VGNC VGNC:106216
Bos taurus SERTAD2 VGNC VGNC:34484
Rattus norvegicus SERTAD2 RGD RGD:1564049
Others SERTAD2 NCBI