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Cat. No.: HY-113891

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JX040

JX040 has an antiviral activity against non-polio enteroviruses, while JX040 has a weak antiviral activity against polioviruses.

For research use only. We do not sell to patients.

CAS No.: 1089596-75-7
Formula: C₁₉H₁₇N₅OS
Molecular Weight:363.44

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (271 KB)

JX040 Chemical Structure

CAS No.: 1089596-75-7

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

JX040 has an antiviral activity against non-polio enteroviruses, while JX040 has a weak antiviral activity against polioviruses^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
LLC-MK2	CC₅₀	>200 μM Compound: JX040	Cytotoxicity against monkey LLC-MK2 cells after 3 to 4 days by crystal violet staining-based spectrophotometric method Cytotoxicity against monkey LLC-MK2 cells after 3 to 4 days by crystal violet staining-based spectrophotometric method	[PMID: 29346733]
Rhabdomyosarcoma cell	CC₅₀	>50 μM Compound: JX040	Cytotoxicity against human RD cells incubated for 3 days by neutral red uptake method Cytotoxicity against human RD cells incubated for 3 days by neutral red uptake method	[PMID: 34085827]

Chemical Information

CAS No. 1089596-75-7
Molecular Weight 363.44
Formula C₁₉H₁₇N₅OS
SMILES

O=C(C1=C2C(N(C(C)C)N=C2)=NC(C3=CC=CS3)=C1)NC4=NC=CC=C4
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (271 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Xing Y, et al. Synthesis and Structure-Activity Relationship (SAR) Studies of Novel Pyrazolopyridine Derivatives as Inhibitors of Enterovirus Replication. J Med Chem. 2018 Feb 22;61(4):1688-1703. [Content Brief]

Calculators

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Dilution Calculator

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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