Cevoglitazar
Based on 1 Customer Validation
Cevoglitazar (LBM-642) is an orally active and highly potent PPARα and PPARγ dual agonist. Cevoglitazar can reduce food intake, body weight, and fasting plasma insulin in obese mice and cynomolgus monkeys. Cevoglitazar has the potential for diabetes and obesity-related disorders research.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 97.00%
- CAS 番号: 839673-52-8
- 分子式: C27H21F3N2O6S
- 分子量:558.53
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
生物活性
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PPARα |
PPARγ |
化学情報
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CAS 番号 839673-52-8
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性状 Solid
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分子量 558.53
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分子式 C27H21F3N2O6S
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Color White to off-white
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SMILES
O=C([C@@H]1N(S(=O)(C2=CC=C(OCC3=C(C)OC(C4=CC=C(C(F)(F)F)C=C4)=N3)C=C2)=O)C5=C(C=CC=C5)C1)O
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別名
LBM-642
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : 50 mg/mL (89.52 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (274 KB)
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SDS (254 KB)
- English - EN (254 KB)
- Français - FR (254 KB)
- Deutsch - DE (254 KB)
- Norwegian - NO (254 KB)
- Español - ES (254 KB)
- Swedish - SV (254 KB)
- Italian - IT (254 KB)
- Korean - KR (254 KB)
- Portuguese - PT (254 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.7904 mL | 8.9521 mL | 17.9041 mL | 44.7604 mL |
| 5 mM | 0.3581 mL | 1.7904 mL | 3.5808 mL | 8.9521 mL | |
| 10 mM | 0.1790 mL | 0.8952 mL | 1.7904 mL | 4.4760 mL | |
| 15 mM | 0.1194 mL | 0.5968 mL | 1.1936 mL | 2.9840 mL | |
| 20 mM | 0.0895 mL | 0.4476 mL | 0.8952 mL | 2.2380 mL | |
| 25 mM | 0.0716 mL | 0.3581 mL | 0.7162 mL | 1.7904 mL | |
| 30 mM | 0.0597 mL | 0.2984 mL | 0.5968 mL | 1.4920 mL | |
| 40 mM | 0.0448 mL | 0.2238 mL | 0.4476 mL | 1.1190 mL | |
| 50 mM | 0.0358 mL | 0.1790 mL | 0.3581 mL | 0.8952 mL | |
| 60 mM | 0.0298 mL | 0.1492 mL | 0.2984 mL | 0.7460 mL | |
| 80 mM | 0.0224 mL | 0.1119 mL | 0.2238 mL | 0.5595 mL |