CGR-50
CGR-50 is a potent RSV fusion glycoprotein (F protein) inhibitor (EC50 = 32.6 nM against RSV A2 in HEp-2 cells). CGR-50 blocks RSV entry by binding to the F protein and inhibiting membrane fusion. CGR-50 can be used for RSV infection research.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 3098857-57-6
- 分子式: C27H30Br2ClFN4O2
- 分子量:656.81
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
製品説明
体外実験
CGR-50 (72 h) demonstrates potent, broad-spectrum activity against a panel of RSV strains (EC50 = 144.7 nM against A1540, EC50 = 354.6 nM against B9320, EC50 = 354.2 nM against B1) in HEp-2 Cells[1].
CGR-50 (72 h) exhibits a CC50 value of 17.0 μM and a selectivity index (SI) of 119.0 in HEp-2 Cells (against the A1540 strain), indicating a favorable safety profile[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 3098857-57-6
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分子量 656.81
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分子式 C27H30Br2ClFN4O2
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SMILES
O=C(N1CCC(C(F)C(N2CCC([C@@H]3C4=C(Br)C=C(Cl)C=C4CCC5=CC(Br)=CN=C53)CC2)=O)CC1)N
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)