DOPE-PEG2000-KAA
DOPE-PEG2000-KAA (DOPE-PEG2000-Mal-CKAAKNK) is an amphiphilic lipid-PEG-peptide conjugate composed of DOPE (1,2-dioleoyl-sn-glycero-3-phosphoethanolamine), PEG2000, and the KAA peptide. KAA peptide functions as a targeting ligand for specific cell or tissue recognition. DOPE-PEG2000-KAA is used for targeted drug delivery through liposome and nanoparticle surface modification.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
DOPE-PEG2000-KAA: surface modification of liposomes and nanoparticles for targeted drug delivery to specific cells or tissues.
Structural composition:
(1) DOPE; a fusogenic phospholipid with two oleoyl chains that anchors into lipid bilayers and promotes pH-responsive membrane fusion for intracellular cargo release;
(2) PEG2000; a hydrophilic polymer that provides steric stabilization, reduces protein adsorption and immune clearance, and extends circulation half-life;
(3) KAA peptide; a targeting peptide that specifically recognizes and binds to receptors or markers on target cells, directing nanocarriers to desired tissues for enhanced drug accumulation and therapeutic efficacy while minimizing off-target toxicity.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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SMILES
[DOPE-PEG2000-KAA]
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別名
DOPE-PEG2000-Mal-CKAAKNK
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)