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製品番号: HY-107054

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ESP-31015

Name: ESP-31015
Brand: MedChemExpress
SKU: HY-107054
Availability: PreOrder

(別名: ETC-1001)

ESP-31015 (ETC-1001) is an orally active and non-fibrate based PPARα agonists. ESP-31015 demonstrates significant lipid-regulating effects in the obese Zucker rat model. ESP-31015 can be used in cardiovascular disease research.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

CAS 番号: 413624-55-2
分子式: C₁₇H₃₄O₃
分子量:286.45

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (263 KB)

ESP-31015 構造式

CAS 番号: 413624-55-2

容量

価格（税別）

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数量

Amount: USD 0.00

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性
- 製品説明
- IC₅₀ & Target
- Cellular Effect
- 体内実験
化学情報
純度とドキュメンテーション
参考文献
Calculators
Help & FAQs
関連分類
Bioz

生物活性

製品説明

IC₅₀ & Target

^[1]

PPARα

PPAR アイソフォーム固有の製品をすべて表示 :

Cellular Effect

Cell Line	Type	Value	Description	References
Hepatocyte	IC₅₀	1.5 μM Compound: 39	Inhibition of lipid synthesis in primary rat hepatocytes by incorporation radiolabeled acetate into cellular lipids Inhibition of lipid synthesis in primary rat hepatocytes by incorporation radiolabeled acetate into cellular lipids	[PMID: 16392818]
Hepatocyte	IC₅₀	4 μM Compound: 14c	Concentration required for inhibition of lipid synthesis in primary cultures of rat hepatocytes Concentration required for inhibition of lipid synthesis in primary cultures of rat hepatocytes	[PMID: 15537362]

体内実験

ESP-31015 (100 mg/kg, p.o., once daily for 2 weeks) shows a 34.6% increase in serum HDL-cholesterol and a 71% reduction in serum triglycerides in female obese Zucker fatty rats^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:

Female obese Zucker fatty rats model^[1]
Dosage:

100 mg/kg
Administration:

Oral administration (p.o.), once daily for 2 weeks
Result:

Showed a 34.6% increase in serum HDL-cholesterol and a 71% reduction in serum triglycerides.

Related Protocols :

化学情報

CAS 番号 413624-55-2
分子量 286.45
分子式 C₁₇H₃₄O₃
SMILES

OCC(C)(C)CCCCC(CCCCC(C)(C)CO)=O
別名

ETC-1001
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (263 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. Pal M, et al. HDL elevators and mimetics--emerging therapies for atherosclerosis. Cardiovasc Hematol Agents Med Chem. 2007 Jan;5(1):55-66. [Content Brief]

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

濃度濃度

体積体積

分子量分子量

希釈計算機

濃度 _(開始) × 体積 _(開始) = 濃度 _(終了) × 体積 _(終了)

濃度 _(開始) 濃度 _(開始)

体積 _(開始) 体積 _(開始)

濃度 _(終了) 濃度 _(終了)

体積 _(終了) 体積 _(終了)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

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MOQ

Minimum order quantity

100 mg

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