FD2157
FD2157 is a photosensitive PI3K inhibitor, with IC50s of 43 nM, 83 nM, 84 nM, 14 nM for PI3Kα, PI3Kβ, PI3Kγ, PI3Kδ respectively. FD2157 potently inhibits cancer cell proliferation and induces cell apoptosis when exposed to 365 nm UV light.
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- CAS 番号: 3046403-79-3
- 分子式: C27H21ClN6O8S
- 分子量:625.01
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
43 nM, 83 nM, 84 nM, 14 nM for PI3Kα, PI3Kβ, PI3Kγ, PI3Kδ[1]
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| B16 | IC50 |
8.8 μM
Compound: FD2157
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Antiproliferative activity against mouse B16 cells assessed as reduction in cell viability incubated for 48 hrs irradiated with 365 nm uv light for 4 min by CCK-8 assay
Antiproliferative activity against mouse B16 cells assessed as reduction in cell viability incubated for 48 hrs irradiated with 365 nm uv light for 4 min by CCK-8 assay
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[PMID: 37634762] |
化学情報
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CAS 番号 3046403-79-3
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分子量 625.01
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分子式 C27H21ClN6O8S
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SMILES
O=C(OCC1=CC(OC)=C(OC)C=C1[N+]([O-])=O)N(N=C2)C(C2=C3)=NC=C3C4=CN=C(Cl)C(NS(=O)(C5=CC=CC=C5)=O)=C4
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
FD2157 関連分類
HY-155996 関連分類
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