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製品番号: HY-137979

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Flunitrazolam

Name: Flunitrazolam
Brand: MedChemExpress
SKU: HY-137979
Price: 215.00 USD
Availability: PreOrder

(別名: FNTZ)

Flunitrazolam (FNTZ) is an orally active triazolobenzodiazepine designer benzodiazepine compound and a positive allosteric modulator of the GABA_A receptor. Flunitrazolam undergoes biometabolic transformation, and 7-amino-flunitrazolam and 7-acetamido-flunitrazolam are its main detectable metabolites in urine. Flunitrazolam can be used in research related to GABA-mediated diseases, such as neurological disorders.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

CAS 番号: 2243815-18-9
分子式: C₁₇H₁₂FN₅O₂
分子量:337.31

保管条件:

Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month

Flunitrazolam 構造式

CAS 番号: 2243815-18-9

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

体外実験

Flunitrazolam (compound 36) acts as a positive allosteric modulator of α1β2γ2 GABA_A receptors in CHO cells, and its activity depends on the classical BZD α⁺/γ2^- binding pocket.^[1]
Flunitrazolam (FNTZ) undergoes biotransformation, and 7-amino-FNTZ and 7-acetamido-FNTZ are its main detectable metabolites in urine; moreover, in human liver microsomes, 7-amino-FNTZ is the only metabolite of flunitrazolam produced under the study conditions^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

化学情報

CAS 番号 2243815-18-9
性状 Solid
分子量 337.31
分子式 C₁₇H₁₂FN₅O₂
Color Light yellow to yellow
SMILES

O=[N+](C1=CC=C(N2C(CN=C3C4=CC=CC=C4F)=NN=C2C)C3=C1)[O-]
別名

FNTZ
輸送条件

Room temperature in continental US; may vary elsewhere.

保管条件

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (294 KB)
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. Norman C, et al. In vitro γ-aminobutyric acid A (GABA) receptor activity and binding interactions at the α/γ interface of 53 prescription and designer benzodiazepines. Communications chemistry. 2026 Apr 07;9(1):155.

[2]. Ameline A, et al. Detection of the designer benzodiazepine flunitrazolam in urine and preliminary data on its metabolism. Drug testing and analysis. 2019 Feb;11(2):223-229.

[3]. Cornett EM, et al. New benzodiazepines for sedation. Best Practice & Research Clinical Anaesthesiology. 2018 Jun 1;32(2):149-64.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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