Ext1 - exostosin glycosyltransferase 1 Gene

Predicted to enable UDP-glycosyltransferase activity and protein dimerization activity. Involved in brain development. Predicted to be located in endoplasmic reticulum. Predicted to be integral component of endoplasmic reticulum membrane. Predicted to be active in Golgi apparatus. Human ortholog(s) of this gene implicated in chondrosarcoma; hereditary multiple exostoses; and trichorhinophalangeal syndrome type II. Orthologous to human EXT1 (exostosin Glycosyltransferase 1). [provided by Alliance of Genome Resources, Apr 2022]