Ptges3 - prostaglandin E synthase 3 Gene

Also Known as p23; Tebp; Ptges; cPGES; sid3177; 5730442A20Rik

生物種: Mus musculus

遺伝子タイプ: protein coding
遺伝子ID: 56351

Summary

Enables DNA Polymerase binding activity. Involved in positive regulation of Telomerase activity; Telomerase holoenzyme complex assembly; and telomere maintenance via Telomerase. Acts upstream of or within several processes, including Glucocorticoid Receptor signaling pathway; glycogen biosynthetic process; and prostaglandin biosynthetic process. Predicted to be located in several cellular components, including actin filament; neuronal cell body; and perinuclear region of cytoplasm. Predicted to be part of chaperone complex and Telomerase holoenzyme complex. Predicted to be active in cytosol and nucleus. Is expressed in several structures, including liver and skin. Orthologous to human PTGES3 (prostaglandin E synthase 3). [provided by Alliance of Genome Resources, Apr 2022]

Ptges3 Products (1)

mRNA Protein Name
NM_019766.4 NP_062740.1 prostaglandin E synthase 3

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence 参考文献 由来
enables DNA polymerase binding IPI
IPI: Inferred from physical interaction
10197982 MGI
Biological Process GO Annotation Evidence 参考文献 由来
acts upstream of or within fibroblast proliferation IMP
IMP: Inferred from mutant phenotype
17438133 MGI
acts upstream of or within glycogen biosynthetic process IMP
IMP: Inferred from mutant phenotype
17438133 MGI
acts upstream of or within lung saccule development IMP
IMP: Inferred from mutant phenotype
17438133 MGI
acts upstream of or within nuclear receptor-mediated glucocorticoid signaling pathway IMP
IMP: Inferred from mutant phenotype
17438133 MGI
acts upstream of or within prostaglandin biosynthetic process IMP
IMP: Inferred from mutant phenotype
17438133 MGI
acts upstream of or within skin development IMP
IMP: Inferred from mutant phenotype
17438133 MGI
involved in telomerase holoenzyme complex assembly IDA
IDA: Inferred from direct assay
10197982 MGI
acts upstream of positive effect telomere maintenance via telomerase IDA
IDA: Inferred from direct assay
10197982 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

prostaglandin E synthase 3

  • cytosolic prostaglandin E2 synthase

  • hsp90 co-chaperone

  • p23 cochaperone

  • progesterone receptor complex p23

  • prostaglandin E synthase 3 (cytosolic)

  • sid 3177

  • telomerase binding protein, p23

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-RS11381 PTGES3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19805 Ptges3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26301 Ptges3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

生物種 Symbol 由来 ID
Homo sapiens Ptges3 NCBI NCBI:10728