SAMD1 - sterile alpha motif domain containing 1 Gene
生物種: Homo sapiens
About SAMD1
This gene has 3 transcripts (splice variants), 1 gene allele, 193 orthologues and 18 paralogues. Ubiquitous expression in colon (RPKM 8.2), brain (RPKM 8.2) and 25 other tissues.
Summary
Predicted to enable chromatin binding activity and histone binding activity. Predicted to be involved in negative regulation of transcription, DNA-templated. Predicted to be located in cytoplasm and extracellular region. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]
SAMD1 Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_138352.3 | NP_612361.1 | sterile alpha motif domain-containing protein 1 |
| Molecular Function GO Annotation | Evidence | 参考文献 | 由来 |
|---|---|---|---|
| enables chromatin binding |
IDA
IDA: Inferred from direct assay
|
33980486 | GOA |
| enables protein binding |
IPI
IPI: Inferred from physical interaction
|
33980486 | GOA |
| Biological Process GO Annotation | Evidence | 参考文献 | 由来 |
|---|---|---|---|
| involved in protein homooligomerization |
IDA
IDA: Inferred from direct assay
|
33980486 | GOA |
| involved in regulation of DNA methylation-dependent heterochromatin formation |
IDA
IDA: Inferred from direct assay
|
33980486 | GOA |
| Cellular Component GO Annotation | Evidence | 参考文献 | 由来 |
|---|---|---|---|
| is active in nucleus |
IDA
IDA: Inferred from direct assay
|
33980486 | GOA |
SAMD1 Protein Structure
SAM_1: SAM domain (Sterile alpha motif) (355 - 411)
- 0
- 100
- 200
- 300
- 400
- 432 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
sterile alpha motif domain-containing protein 1 |
|
Orthologs Information
| 生物種 | Symbol | 由来 | ID |
|---|---|---|---|
| Rattus norvegicus | SAMD1 | RGD | RGD:7529921 |
| Mus musculus | SAMD1 | MGD | MGI:2142433 |
| Others | SAMD1 | NCBI |