PTER - phosphotriesterase related Gene

Also Known as HPHRP; RPR-1

生物種: Homo sapiens

遺伝子タイプ: protein coding

遺伝子ID: 9317

About PTER

Cytogenetic location: 10p13 Genomic coordinates (GRCh38): 10:16,437,010-16,519,020 (from NCBI)

This gene has 5 transcripts (splice variants) and 205 orthologues. Ubiquitous expression in kidney (RPKM 11.0), brain (RPKM 10.8) and 25 other tissues.

Summary

Predicted to enable hydrolase activity, acting on ester bonds and zinc ion binding activity. Involved in epithelial cell differentiation. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022]

PTER Products (5)

mRNA	Protein	Name
NM_001001484.3	NP_001001484.1	phosphotriesterase-related protein isoform 1
NM_001261836.2	NP_001248765.1	phosphotriesterase-related protein isoform 1
NM_001261837.2	NP_001248766.1	phosphotriesterase-related protein isoform 2
NM_001261838.2	NP_001248767.1	phosphotriesterase-related protein isoform 3
NM_030664.5	NP_109589.2	phosphotriesterase-related protein isoform 1

Gene Ontology

Molecular Function
Biological Process

Molecular Function GO Annotation	Evidence	参考文献	由来
enables protein binding	IPI IPI: Inferred from physical interaction	32296183	GOA

Biological Process GO Annotation	Evidence	参考文献	由来
involved in epithelial cell differentiation	IEP IEP: Inferred from expression pattern	21492153	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

PTER Protein Structure

PTE

0
100
200
300
349 a.a.

Protein Preferred Names	Protein Names
phosphotriesterase-related protein	parathion hydrolase-related protein

PTER Protein-protein interaction Information

Type	タンパク質名	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	参考文献
Intra	PTER	Q96BW5	GSC2	Homo sapiens	O15499	Y2H Prey Pooling	32296183
Intra	PTER	Q96BW5	GSC2	Homo sapiens	O15499	Y2H Array	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

関連疾患

Diseases	Alias
Mucinous Bronchioloalveolar Adenocarcinoma	Bronchiolo-Alveolar Carcinoma, Mucinous
Dihydropyrimidinase Deficiency	Dihydropyrimidinuria Dpys Deficiency Dph Deficiency DPYSD Dihydrouracil Amidohydrolase Deficiency Dihydropyrimidinuria Due To Dpys Deficiency
Bjornstad Syndrome	BJS Pili Torti And Nerve Deafness Ptd Pili Torti-Deafness Syndrome Deafness-Pili Torti-Hypogonadism Syndrome Deafness And Pili Torti, Bjornstad Type Pili Torti-Sensorineural Hearing Loss Björnstad Syndrome Ptnd Hearing Loss-Pili Torti-Hypogonadism Syndrome Bjoernstad Syndrome
Secondary Syphilis	Syphilis, Secondary Secondary Syphilis Of Viscera Or Bone

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)

製品番号	製品名	製品効果	純度	Rare Diseases
HY-157126	Pterostilbene-isothiocyanate	Inhibitor	/	Unkown
HY-185341	PTERi	Inhibitor	98.04%	Unkown
HY-RS11366	PTER Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS18495	Pter Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS24977	Pter Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

生物種	Symbol	由来	ID
Felis catus	PTER	VGNC	VGNC:69140
Rattus norvegicus	PTER	RGD	RGD:61313
Mus musculus	PTER	MGD	MGI:107372
Canis familiaris	PTER	VGNC	VGNC:45139
Macaca mulatta	PTER	VGNC	VGNC:76466
Bos taurus	PTER	VGNC	VGNC:33497
Others	PTER	NCBI