Gontivimab
Based on 1 Customer Validation
Gontivimab (ALX-0171; VR-465) is a poent anti-RSV prefusion F protein nanobody with a KD value of 0.113 nM. Gontivimab shows antiviral activity. Gontivimab reduces the RSV load in the nose and lung.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 95.11%
- CAS 番号: 1257358-38-5
- 分子量:43.12 kDa
-
保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
VH-VH-VH
Human
RSV-F
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
-
Animal Model:Rats (RSV Tracy)[1]
-
Dosage:1-68 mg/kg
-
Administration:Intranasal administration or nebulization; once (day 2 or day 3) or twice (day 2 and day 3)
-
Result:Resulted in significant viral load reductions in the lungs ranging.
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
A0A0X8XRK2
Unconjugated
The product can be reconstituted/diluted with sterile PBS or saline.
-
VH-VH-VH
ELISA, FACS, Functional assay
化学情報
-
CAS 番号 1257358-38-5
-
性状 Liquid
-
分子量 43.12 kDa
-
Color Colorless to light yellow
-
SMILES
[Gontivimab]
-
別名
ALX-0171; VR-465
-
輸送条件
Shipping with dry ice.
-
Formulation
Please refer to the lot-specific COA for specific buffer information.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
-
データシート (257 KB)
-
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
-
Inhibitory Antibodies User Guide (603 KB)
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)