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製品番号: HY-N20749

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Hericene C

Hericene C is a geranyl resorcinol metabolite. Hericene C exerts a protective effect against Thapsigargin-induced endoplasmic reticulum stress-dependent cell death. Hericene C can be used for research on neurodegenerative diseases.

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CAS 番号: 157207-56-2
分子式: C₃₇H₆₀O₅
分子量:584.87

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Hericene C 構造式

CAS 番号: 157207-56-2

価格（税別）

Amount: USD 0.00

* アイテムを追加する前、数量をご選択ください

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

体外実験

Endoplasmic Reticulum Stress

Hericene C (2c) (0-100; 24 h) exhibits moderate protective activity against Thapsigargin (HY-13433)-induced ER stress-dependent cell death in Neuro2a cells^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability Assay^[2]

Cell Line:

Neuro2a
Concentration:

0, 10, 30, 100 μM
Incubation Time:

24 h
Result:

Exhibited moderate protective activity against TG-induced ER stress at concentrations above 30 μM.
Showed no significant protection against TM-induced ER stress.
Regioisomers 7b and 7c increased cell viability by approximately 20% at 10 μM in TM-induced ER stressed cells.

Related Protocols :

化学情報

CAS 番号 157207-56-2
分子量 584.87
分子式 C₃₇H₆₀O₅
SMILES

CCCCCCCCCCCCCCCCCC(OCC1=C(C=O)C(O)=C(C/C=C(CC/C=C(C)/C)\C)C(OC)=C1)=O
Structure Classification
- Others
Initial Source
- Microorganism
Hericium erinaceum
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

取扱説明書 (2659 KB)

参考文献

[1]. Corana F, et al. Array of Metabolites in Italian Hericium erinaceus Mycelium, Primordium, and Sporophore. Molecules. 2019 Sep 27;24(19):3511.

[2]. Kobayashi S, et al. Total syntheses and endoplasmic reticulum stress suppressive activities of hericenes A− C and their derivatives. Tetrahedron Letters. 2018 May 2;59(18):1733-6.

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

濃度濃度

体積体積

分子量分子量

希釈計算機

濃度 _(開始) × 体積 _(開始) = 濃度 _(終了) × 体積 _(終了)

濃度 _(開始) 濃度 _(開始)

体積 _(開始) 体積 _(開始)

濃度 _(終了) 濃度 _(終了)

体積 _(終了) 体積 _(終了)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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