JNK-IN-13
Based on 1 Customer Validation
JNK-IN-13 (compound 1) is a potent and selective JNK inhibitor with IC50s of 290 nM and 500 nM for JNK3 and JNK2, respectively.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 97.60%
- CAS 番号: 345986-38-1
- 分子式: C13H7ClN4S
- 分子量:286.74
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保管条件:
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
生物活性
製品説明
IC50 & Target
[1]|
JNK2 500 nM (IC50) |
JNK3 290 nM (IC50) |
化学情報
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CAS 番号 345986-38-1
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性状 Solid
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分子量 286.74
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分子式 C13H7ClN4S
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Color White to yellow
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SMILES
ClC1=NC(C(C2=NC3=CC=CC=C3S2)C#N)=CC=N1
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
溶剤 & 溶解度
体外:
DMSO : ≥ 31 mg/mL (108.11 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (272 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.4875 mL | 17.4374 mL | 34.8748 mL | 87.1870 mL |
| 5 mM | 0.6975 mL | 3.4875 mL | 6.9750 mL | 17.4374 mL | |
| 10 mM | 0.3487 mL | 1.7437 mL | 3.4875 mL | 8.7187 mL | |
| 15 mM | 0.2325 mL | 1.1625 mL | 2.3250 mL | 5.8125 mL | |
| 20 mM | 0.1744 mL | 0.8719 mL | 1.7437 mL | 4.3594 mL | |
| 25 mM | 0.1395 mL | 0.6975 mL | 1.3950 mL | 3.4875 mL | |
| 30 mM | 0.1162 mL | 0.5812 mL | 1.1625 mL | 2.9062 mL | |
| 40 mM | 0.0872 mL | 0.4359 mL | 0.8719 mL | 2.1797 mL | |
| 50 mM | 0.0697 mL | 0.3487 mL | 0.6975 mL | 1.7437 mL | |
| 60 mM | 0.0581 mL | 0.2906 mL | 0.5812 mL | 1.4531 mL | |
| 80 mM | 0.0436 mL | 0.2180 mL | 0.4359 mL | 1.0898 mL | |
| 100 mM | 0.0349 mL | 0.1744 mL | 0.3487 mL | 0.8719 mL |