KCC2 Modulator-3
Based on 1 Customer Validation
KCC2 Modulator-3 (example 54) is a KCC2 modulator. KCC2 Modulator-3 is used for the research of neurological disorders.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 98.84%
- CAS 番号: 2704531-38-2
- 分子式: C35H39N7O3
- 分子量:605.73
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保管条件:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
製品説明
体外実験
KCC2 is the only specific Cl- efflux transporter in mature neurons, which determines the inhibitory function of GABA; decreased expression/activity leads to neuronal hyperexcitability, making it a common core target for epilepsy, neuropathic pain and developmental encephalopathy.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 2704531-38-2
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性状 Solid
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分子量 605.73
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分子式 C35H39N7O3
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Color Off-white to light yellow
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SMILES
O=C1C2=C(CN1C(C)C)C(NC3=CC=C(C4=CC=C(OCCC5(CCC#C)N=N5)C=C4)C=C3)=NC(N6CCOC(C7CC7)C6)=N2
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
溶剤 & 溶解度
体外:
DMSO : 50 mg/mL (82.55 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (269 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.6509 mL | 8.2545 mL | 16.5090 mL | 41.2725 mL |
| 5 mM | 0.3302 mL | 1.6509 mL | 3.3018 mL | 8.2545 mL | |
| 10 mM | 0.1651 mL | 0.8255 mL | 1.6509 mL | 4.1273 mL | |
| 15 mM | 0.1101 mL | 0.5503 mL | 1.1006 mL | 2.7515 mL | |
| 20 mM | 0.0825 mL | 0.4127 mL | 0.8255 mL | 2.0636 mL | |
| 25 mM | 0.0660 mL | 0.3302 mL | 0.6604 mL | 1.6509 mL | |
| 30 mM | 0.0550 mL | 0.2752 mL | 0.5503 mL | 1.3758 mL | |
| 40 mM | 0.0413 mL | 0.2064 mL | 0.4127 mL | 1.0318 mL | |
| 50 mM | 0.0330 mL | 0.1651 mL | 0.3302 mL | 0.8255 mL | |
| 60 mM | 0.0275 mL | 0.1376 mL | 0.2752 mL | 0.6879 mL | |
| 80 mM | 0.0206 mL | 0.1032 mL | 0.2064 mL | 0.5159 mL |
KCC2 Modulator-3 関連分類
HY-160083 関連分類
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