L 708286

L 708286 (DFKi) shows a high degree of three-dimensional structural consistency with the TOMI fragment (Ala-15-Tyr-20) (based on molecular shape matching analysis of crystallographic data), with a maximum spatial overlap volume of 65.4 to 95.4 Å^3[1].
L 708286 shows a high degree of conformational agreement with the full-length TOMI protein, as determined by molecular shape matching analysis based on crystallographic data. Under different atomic radius parameters (SA-UA and vdW-UA), the maximum spatial overlap volumes between the two are 86.4 ų and 325.5 ų, respectively^[1].
L 708286 shows a high degree of spatial conformational agreement with the full-length relaxed TOMI protein (as determined by three-dimensional molecular shape matching analysis based on crystallographic data), representing one of the highest-scoring hits, with a spatial overlap volume of 63.4 ų under the SA-UA parameter^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.