OT-7100
OT-7100 is an orally active analgesic agent. OT-7100 inhibits hyperalgesia possibly by enhancing adenosinergic neurotransmission in the dorsal horn. OT-7100 can be used for the researches of inflammation, neurological and metabolic disease such as diabetes2].
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 174858-27-6
- 分子式: C20H24N4O4
- 分子量:384.43
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
Adenosine Receptor アイソフォーム固有の製品をすべて表示
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生物活性
製品説明
体外実験
体内実験
OT-7100 (10-100 mg/kg, p.o., daily for 21 days) increases the nociceptive threshold in diabetic rats[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 174858-27-6
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分子量 384.43
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分子式 C20H24N4O4
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SMILES
O=C(C1=CC(OC)=C(OC)C(OC)=C1)NC2=CC(CCCC)=NC3=CC=NN23
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Yasuda T, et al. A novel analgesic compound OT-7100 attenuates nociceptive responses in animal models of inflammatory and neuropathic hyperalgesia: a possible involvement of adenosinergic anti-nociception. Jpn J Pharmacol. 2001 Nov;87(3):214-25. [Content Brief]
[2]. Miki S, et al. Antinociceptive effect of the novel compound OT-7100 in a diabetic neuropathy model. Eur J Pharmacol. 2001 Nov 2;430(2-3):229-34. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)