PF-06445974 precursor
Based on 1 Customer Validation
PF-06445974 precursor (Compound 28) is a nitro precursor and synthetic intermediate. PF-06445974 precursor can be used for the synthesis of PF-06445974 (HY-119190). PF-06445974 is a positron emission tomography (PET) compound that acts potently on PDE4B.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.67%
- CAS 番号: 2055777-51-8
- 分子式: C20H15N5O3
- 分子量:373.36
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保管条件:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
生物活性
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PDE4B |
化学情報
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CAS 番号 2055777-51-8
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性状 Solid
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分子量 373.36
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分子式 C20H15N5O3
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Color Yellow to green
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SMILES
N#CC1=C([N+]([O-])=O)C=C(C2=C(C(N(C3CC3)CC4)=O)N4C5=C2N=CC=C5)C=C1
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
溶剤 & 溶解度
DMSO : 50 mg/mL (133.92 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (278 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.6784 mL | 13.3919 mL | 26.7838 mL | 66.9595 mL |
| 5 mM | 0.5357 mL | 2.6784 mL | 5.3568 mL | 13.3919 mL | |
| 10 mM | 0.2678 mL | 1.3392 mL | 2.6784 mL | 6.6960 mL | |
| 15 mM | 0.1786 mL | 0.8928 mL | 1.7856 mL | 4.4640 mL | |
| 20 mM | 0.1339 mL | 0.6696 mL | 1.3392 mL | 3.3480 mL | |
| 25 mM | 0.1071 mL | 0.5357 mL | 1.0714 mL | 2.6784 mL | |
| 30 mM | 0.0893 mL | 0.4464 mL | 0.8928 mL | 2.2320 mL | |
| 40 mM | 0.0670 mL | 0.3348 mL | 0.6696 mL | 1.6740 mL | |
| 50 mM | 0.0536 mL | 0.2678 mL | 0.5357 mL | 1.3392 mL | |
| 60 mM | 0.0446 mL | 0.2232 mL | 0.4464 mL | 1.1160 mL | |
| 80 mM | 0.0335 mL | 0.1674 mL | 0.3348 mL | 0.8370 mL | |
| 100 mM | 0.0268 mL | 0.1339 mL | 0.2678 mL | 0.6696 mL |