RP-001
RP-001 is a picomolar short-acting S1P1 (EDG1) selective agonist, with an EC50 of 9 pM. RP-00 induces internalization and polyubiquitination of S1P1. RP-001 has little activity on S1P2-S1P4 and only moderate affinity for S1P5.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 1306761-53-4
- 分子式: C24H24N4O4
- 分子量:432.47
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
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HY-108496
Sphingosine-1-phosphateS1PR Agonist -
HY-10968
CYM5442S1P1 Receptor Agonist -
HY-108490
VPC 23019S1P1/3 Antagonist -
HY-W008947
SEW2871S1P1 Agonist -
HY-101395
W146S1PR1 Antagonist -
HY-108494
CYM50260S1P4 Receptor Agonist -
HY-10968R
CYM5442 (Standard)S1P1 Receptor Agonist -
HY-108493
CS-2100S1P1 Agonist -
HY-108490R
VPC 23019 (Standard)Reference Standard -
HY-12835
S1P1 agonist IIIS1P1 Agonist -
HY-108491
N,N-DimethylsphingosineSphingosine Kinase Inhibitor -
HY-100675
JTE-013S1P2 Antagonist
生物活性
製品説明
体外実験
体内実験
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
臨床実験
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
化学情報
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CAS 番号 1306761-53-4
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分子量 432.47
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分子式 C24H24N4O4
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SMILES
O=C(O)CCNC1CCC2=C1C=CC=C2C3=NOC(C4=CC=C(OC(C)C)C(C#N)=C4)=N3
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
RP-001 関連分類
HY-101939 関連分類
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