RP-001 hydrochloride
Based on 1 Customer Validation
RP-001 hydrochloride is a picomolar short-acting S1P1 (EDG1) selective agonist, with an EC50 of 9 pM. RP-00 hydrochloride induces internalization and polyubiquitination of S1P1. RP-001 hydrochloride has little activity on S1P2-S1P4 and only moderate affinity for S1P5.
For research use only. We do not sell to patients.
- Purity: 98.8%
- CAS No.: 1781880-34-9
- Formula: C24H25ClN4O4
- Molecular Weight:468.93
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Storage:
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1781880-34-9
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Appearance Solid
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Molecular Weight 468.93
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Formula C24H25ClN4O4
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Color White to off-white
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SMILES
O=C(O)CCNC1CCC2=C1C=CC=C2C3=NOC(C4=CC=C(OC(C)C)C(C#N)=C4)=N3.Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Solvent & Solubility
DMSO : 29.4 mg/mL (62.70 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (273 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.1325 mL | 10.6626 mL | 21.3251 mL | 53.3129 mL |
| 5 mM | 0.4265 mL | 2.1325 mL | 4.2650 mL | 10.6626 mL | |
| 10 mM | 0.2133 mL | 1.0663 mL | 2.1325 mL | 5.3313 mL | |
| 15 mM | 0.1422 mL | 0.7108 mL | 1.4217 mL | 3.5542 mL | |
| 20 mM | 0.1066 mL | 0.5331 mL | 1.0663 mL | 2.6656 mL | |
| 25 mM | 0.0853 mL | 0.4265 mL | 0.8530 mL | 2.1325 mL | |
| 30 mM | 0.0711 mL | 0.3554 mL | 0.7108 mL | 1.7771 mL | |
| 40 mM | 0.0533 mL | 0.2666 mL | 0.5331 mL | 1.3328 mL | |
| 50 mM | 0.0427 mL | 0.2133 mL | 0.4265 mL | 1.0663 mL | |
| 60 mM | 0.0355 mL | 0.1777 mL | 0.3554 mL | 0.8885 mL |
RP-001 hydrochloride Related Classifications
HY-101939A Related Classifications
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