1781880-34-9
Chemical Structure
RP-001 hydrochloride
- CAS No.: 1781880-34-9
- Formula:C24H25ClN4O4
- Molecular Weight:468.93
IUPAC Name: 3-((4-(5-(3-cyano-4-isopropoxyphenyl)-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1H-inden-1-yl)amino)propanoic acid hydrochloride
InChIKey: ZHPGSGYEFGEZAL-UHFFFAOYSA-N
SMILES: O=C(O)CCNC1CCC2=C1C=CC=C2C3=NOC(C4=CC=C(OC(C)C)C(C#N)=C4)=N3.Cl
Biological Activity: RP-001 hydrochloride is a picomolar short-acting S1P1 (EDG1) selective agonist, with an EC50 of 9 pM. RP-00 hydrochloride induces internalization and polyubiquitination of S1P1. RP-001 hydrochloride has little activity on S1P2-S1P4 and only moderate affinity for S1P5[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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RP-001 hydrochloride | 98.8% | RP-001 hydrochloride is a picomolar short-acting S1P1 (EDG1) selective agonist, with an EC50 of 9 pM. RP-00 hydrochloride induces internalization and polyubiquitination of S1P1. RP-001 hydrochloride has little activity on S1P2-S1P4 and only moderate affinity for S1P5. | ||||||||||||||||||||
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Keywords
