8 Results for "

Y1-R

" in MedChemExpress (MCE) Product Catalog:
Products (8)

8 Results for "Y1-R" in MCE Product Catalog:

製品番号: HY-P11043
GEP44 is a peptide biased triple agonist targeting Glucagon-like peptide 1 receptor (GLP-1R), neuropeptide Y1 Receptor (Y1-R), and neuropeptide Y2 Receptor (Y2-R). GEP44 induces Y1-R antagonist-controlled, GLP-1R-dependent stimulation of insulin secretion in both rat and human pancreatic islets by counteracting effects of Y1-R and GLP-1R agonism. GEP44 promotes insulin-independent Y1-R-mediated glucose uptake in muscle tissue and significantly reduces food intake and body weight in diet-induced obese rat models. GEP44 can be used for obesity and type 2 diabetes mellitus research [1].
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製品番号: HY-145837
CAS 番号: 2773476-41-6
研究分野:  

Cancer

Y1R probe-1 (Compound 39) is a high-affinity fluorescence probe for the Neuropeptide Y Y1 Receptor. Y1R probe-1 has the potential for the research of cancer disease [1].
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製品番号: HY-179133
CAS 番号: 3021527-82-9
Target:  

P2Y Receptor PKA Raf MEK ERK

研究分野:  

Inflammation/Immunology

HDB-1 is a selective inhibitor of the P2Y14 receptor (P2Y14R) with an IC50 of 26 pM. HDB-1 shows no significant inhibition on P2Y1R, P2Y2R, P2Y4R, P2Y6R, and P2Y12R. HDB-1 blocks the activation of hepatic stellate cells (HSC) by inhibiting the PKA/Raf1/MEK/ERK signaling pathway mediated by P2Y14R, thereby alleviating the core pathological process of liver fibrosis. HDB-1 can be used for the study of liver fibrosis [1].
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製品番号: HY-144603
CAS 番号: 2773476-40-5
Neuropeptide Y Y1 receptor antagonist 1 (compound 39), a fluorescent probe, is a potent antagonist of neuropeptide Y Y 1 receptor (Y 1R), with a Ki of 0.19 nM [1].
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製品番号: HY-P10545
研究分野:  

Neurological Disease

[D-His26]-Neuropeptide Y, human, rat is a synthetic variant of neuropeptide Y (NPY). [D-His26]-Neuropeptide Y, human, rat acts as a Y1R agonist that can prevent the development of anxiety, social impairment, and depressive symptoms, and has the potential to be used as an early intervention treatment for post-traumatic stress reactions [1].
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製品番号: HY-P11044
研究分野:  

Metabolic Disease

GEP12 is a GLP-1R/Y1-R/Y2-R tri-receptor agonist peptide with an EC50 of 17.3 nM and an IC50 of 19.2 nM for receptor binding. GEP12 may promote glycemic control and weight loss [1].
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製品番号: HY-RS09512

Npy1r Mouse Pre-designed siRNA Set A contains three designed siRNAs for Npy1r gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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製品番号: HY-N18260
CAS 番号: 60010-74-4
Desmodilactone is a P2Y1R allosteric antagonist. Desmodilactone can be used for the research of thrombosis [1] .
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