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United States

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Total: USD 0.00 Checkout

製品番号: HY-187359

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SR-B-182

SR-B-182 is a SARS-CoV-2 main protease (M_Pro) inhibitor with an IC₅₀ of 0.015 μM. SR-B-182 can be used for the research of COVID-19.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

分子式: C₉H₅N₅O₃
分子量:231.17

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

SR-B-182 構造式

価格（税別）

Amount: USD 0.00

* アイテムを追加する前、数量をご選択ください

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

SR-B-182 is a SARS-CoV-2 main protease (M_Pro) inhibitor with an IC₅₀ of 0.015 μM. SR-B-182 can be used for the research of COVID-19^[1].

体外実験

SR-B-182 acts via a covalent mechanism based on nucleophilic aromatic substitution (SNAr), forming a covalent adduct with Cys145 at the catalytic site of MPro without causing steric hindrance conflict with the aa187-189 loop of MPro.^[1]

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

化学情報

分子量 231.17
分子式 C₉H₅N₅O₃
SMILES

O=[N+](C1=NON=C1C2=NC3=CC=CC=C3N2)[O-]
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

取扱説明書 (2659 KB)

参考文献

[1]. Sandeep Atla, et al. High-Throughput Screening Identifies Covalent Inhibitors with Unique Chemistry and Binding Modes for SARS-CoV-2 Main Protease. JACS Au 2026.

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

濃度濃度

体積体積

分子量分子量

希釈計算機

濃度 _(開始) × 体積 _(開始) = 濃度 _(終了) × 体積 _(終了)

濃度 _(開始) 濃度 _(開始)

体積 _(開始) 体積 _(開始)

濃度 _(終了) 濃度 _(終了)

体積 _(終了) 体積 _(終了)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Keywords

MOQ

Minimum order quantity

100 mg

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