TH-Z145
Based on 1 Customer Validation
TH-Z145, a lipophilic bisphosphonate, is a FPPS inhibitor (IC50: 210 nM).
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.69%
- CAS 番号: 2260887-57-6
- 分子式: C16H28O7P2
- 分子量:394.34
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
FPPS[1]
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:B16-OVA cells (s.c.) xenograft mice model[1].
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Dosage:20 μg
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Administration:Intraperitoneal injection (i.p.)
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Result:Inhibited tumor growth and prolonged survival.
化学情報
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CAS 番号 2260887-57-6
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性状 Solid
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分子量 394.34
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分子式 C16H28O7P2
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Color Off-white to light yellow
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SMILES
O=P(O)(C(P(O)(O)=O)CC1=CC(OCCCCCCCC)=CC=C1)O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : 100 mg/mL (253.59 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (268 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Portuguese - PT (251 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.5359 mL | 12.6794 mL | 25.3588 mL | 63.3971 mL |
| 5 mM | 0.5072 mL | 2.5359 mL | 5.0718 mL | 12.6794 mL | |
| 10 mM | 0.2536 mL | 1.2679 mL | 2.5359 mL | 6.3397 mL | |
| 15 mM | 0.1691 mL | 0.8453 mL | 1.6906 mL | 4.2265 mL | |
| 20 mM | 0.1268 mL | 0.6340 mL | 1.2679 mL | 3.1699 mL | |
| 25 mM | 0.1014 mL | 0.5072 mL | 1.0144 mL | 2.5359 mL | |
| 30 mM | 0.0845 mL | 0.4226 mL | 0.8453 mL | 2.1132 mL | |
| 40 mM | 0.0634 mL | 0.3170 mL | 0.6340 mL | 1.5849 mL | |
| 50 mM | 0.0507 mL | 0.2536 mL | 0.5072 mL | 1.2679 mL | |
| 60 mM | 0.0423 mL | 0.2113 mL | 0.4226 mL | 1.0566 mL | |
| 80 mM | 0.0317 mL | 0.1585 mL | 0.3170 mL | 0.7925 mL | |
| 100 mM | 0.0254 mL | 0.1268 mL | 0.2536 mL | 0.6340 mL |
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