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製品番号: HY-187835

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WO677

WO677 is a KCNT1 inhibitor that can be used in studies of nervous system disorders associated with KCNT1 function, such as epilepsy.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

CAS 番号: 3088105-77-2
分子式: C₁₈H₁₄F₆N₆O₂
分子量:460.33

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

WO677 構造式

CAS 番号: 3088105-77-2

価格（税別）

Amount: USD 0.00

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

WO677 is a KCNT1 inhibitor that can be used in studies of nervous system disorders associated with KCNT1 function, such as epilepsy^[1].

体外実験

WO677 (I‑1a) exhibits an IC₅₀ ≤ 250 nM in the FLIPR calcium flux inhibition assay^[1].
WO677 can be obtained via trifluoroacetic acid treatment, palladium-catalyzed C-N coupling, titanium-mediated imine formation, and diastereomeric intermediate conversion^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

化学情報

CAS 番号 3088105-77-2
分子量 460.33
分子式 C₁₈H₁₄F₆N₆O₂
SMILES

CN1N=C(C(F)(F)F)C=C1C(N[C@H]2COCC3=NN(C4=CC(C(F)(F)F)=NC=C4)C=C32)=O
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

取扱説明書 (2659 KB)

参考文献

[1]. Stock N S. Heterocyclic compounds useful as kcnt1 inhibitors. WO2025117677A1, WIPO, 2025.

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モル濃度計算機

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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