country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Cat. No.: HY-161021

Copy Link Print Information

AC2 selective-IN-1

AC2 selective-IN-1 (compound 14) is a? potent (IC₅₀=4.45 μM), non-toxic, and selective mAC2 inhibitor.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

화학식: C₄₁H₄₇N₈O₈P
분자량:810.83

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (276 KB)

AC2 selective-IN-1 Chemical Structure

Amount: USD 0.00

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- Cellular Effect
Chemical Information
Protocol (1)
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

AC2 selective-IN-1 (compound 14) is a? potent (IC₅₀=4.45 μM), non-toxic, and selective mAC2 inhibitor^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
CCRF-CEM	IC₅₀	>10 μM Compound: 14	Cytotoxicity against human CCRF-CEM cells by CellTiter-Glo 2.0 assay Cytotoxicity against human CCRF-CEM cells by CellTiter-Glo 2.0 assay	[PMID: 37931521]
HeLa S3	IC₅₀	>10 μM Compound: 14	Cytotoxicity against human HeLa S3 cells by CellTiter-Glo 2.0 assay Cytotoxicity against human HeLa S3 cells by CellTiter-Glo 2.0 assay	[PMID: 37931521]
HepG2	IC₅₀	>10 μM Compound: 14	Cytotoxicity against human HepG2 cells by CellTiter-Glo 2.0 assay Cytotoxicity against human HepG2 cells by CellTiter-Glo 2.0 assay	[PMID: 37931521]
HL-60	IC₅₀	10 μM Compound: 14	Cytotoxicity against human HL-60 cells by CellTiter-Glo 2.0 assay Cytotoxicity against human HL-60 cells by CellTiter-Glo 2.0 assay	[PMID: 37931521]
NHDF	IC₅₀	>10 μM Compound: 14	Cytotoxicity against human NHDF cells by CellTiter-Glo 2.0 assay Cytotoxicity against human NHDF cells by CellTiter-Glo 2.0 assay	[PMID: 37931521]

Chemical Information

분자량 810.83
화학식 C₄₁H₄₇N₈O₈P
SMILES

NC1=C2C(N(CCOCP(N[C@H](C(OC(C)C)=O)CC3=CC=CC=C3)(N[C@@H](CC4=CC=CC=C4)C(OC(C)C)=O)=O)C=C2C5=CC=CC(C(N6)=NOC6=O)=C5)=NC=N1
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

Protocol

All Cell Biology

Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (276 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Pavel Kraina, et al. Discovery of a potent and selective human AC2 inhibitor based on 7-deazapurine analogues of adefovir. Bioorg Med Chem. 2023. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

견적 받기 해외재고보유

Other size

견적 받기