COX-1/2-IN-9
COX-1/2-IN-9 (Compound 3n) is a potent and selective inhibitor of COX-1/2, with IC50 values of 0.031 µM and 0.01 µM, respectively. COX-1/2-IN-9 possesses both antibacterial and anti-inflammatory activities, effectively inhibiting MRSA 1478 (MIC=50 μg/mL) and multidrug-resistant S. lentus (MIC=50 μg/mL). COX-1/2-IN-9 holds significant potential to alleviate MRSA-induced pneumonia in immunocompromised states.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- 화학식: C30H20IN9O13S2
- 분자량:905.57
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
제품 설명
IC50 & Target
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COX-1 0.031 μM (IC50) |
COX-2 0.010 μM (IC50) |
Chemical Information
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분자량 905.57
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화학식 C30H20IN9O13S2
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SMILES
IC1=CC2=C(N=C(SCC(NC3=CC=C([N+]([O-])=O)C=C3[N+]([O-])=O)=O)N(C4=CC=C(S(=O)(NCC(NC5=CC=C([N+]([O-])=O)C=C5[N+]([O-])=O)=O)=O)C=C4)C2=O)C=C1
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
COX-1/2-IN-9 Related Classifications
HY-162761 Related Classifications
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