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Cat. No.: HY-168103

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FBPase-IN-3

FBPase-IN-3 (compound 45) is a FBPase (fructose-1,6-bisphosphatase) inhibitor with an IC₅₀ of 2.08 μM. FBPase-IN-3 exhibits potent inhibitory activity of gluconeogenesis.

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CAS No.: 3102011-46-8
화학식: C₂₁H₁₆ClN₃O₄S
분자량:441.89

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

FBPase-IN-3 Chemical Structure

CAS No.: 3102011-46-8

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

제품 설명

FBPase-IN-3 (compound 45) is a FBPase (fructose-1,6-bisphosphatase) inhibitor with an IC₅₀ of 2.08 μM. FBPase-IN-3 exhibits potent inhibitory activity of gluconeogenesis^[1].

Chemical Information

CAS No. 3102011-46-8
분자량 441.89
화학식 C₂₁H₁₆ClN₃O₄S
SMILES

O=C(NS(=O)(C1=CC=C(OC)C=C1)=O)C2=CC(Cl)=CC(C3=NC4=CC=CC=C4N3)=C2
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Huahao Wang, et al. Discovery of novel fructose-1,6-bisphosphatase inhibitors bearing benzimidazole scaffold using a dual-ligand molecular docking model. Eur J Med Chem. 2024 Sep 19:279:116888. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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