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Cat. No.: HY-137979

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Flunitrazolam

Name: Flunitrazolam
Brand: MedChemExpress
SKU: HY-137979
Price: 215.00 USD
Availability: PreOrder

(Synonyms: FNTZ)

Flunitrazolam (FNTZ) is an orally active triazolobenzodiazepine designer benzodiazepine compound and a positive allosteric modulator of the GABA_A receptor. Flunitrazolam undergoes biometabolic transformation, and 7-amino-flunitrazolam and 7-acetamido-flunitrazolam are its main detectable metabolites in urine. Flunitrazolam can be used in research related to GABA-mediated diseases, such as neurological disorders.

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CAS No.: 2243815-18-9
화학식: C₁₇H₁₂FN₅O₂
분자량:337.31

보관:

Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month

Flunitrazolam Chemical Structure

CAS No.: 2243815-18-9

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- In Vitro
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

In Vitro

Flunitrazolam (compound 36) acts as a positive allosteric modulator of α1β2γ2 GABA_A receptors in CHO cells, and its activity depends on the classical BZD α⁺/γ2^- binding pocket.^[1]
Flunitrazolam (FNTZ) undergoes biotransformation, and 7-amino-FNTZ and 7-acetamido-FNTZ are its main detectable metabolites in urine; moreover, in human liver microsomes, 7-amino-FNTZ is the only metabolite of flunitrazolam produced under the study conditions^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 2243815-18-9
Appearance Solid
분자량 337.31
화학식 C₁₇H₁₂FN₅O₂
Color Light yellow to yellow
SMILES

O=[N+](C1=CC=C(N2C(CN=C3C4=CC=CC=C4F)=NN=C2C)C3=C1)[O-]
Synonyms

FNTZ
선적

Room temperature in continental US; may vary elsewhere.

보관

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (294 KB)
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Norman C, et al. In vitro γ-aminobutyric acid A (GABA) receptor activity and binding interactions at the α/γ interface of 53 prescription and designer benzodiazepines. Communications chemistry. 2026 Apr 07;9(1):155.

[2]. Ameline A, et al. Detection of the designer benzodiazepine flunitrazolam in urine and preliminary data on its metabolism. Drug testing and analysis. 2019 Feb;11(2):223-229.

[3]. Cornett EM, et al. New benzodiazepines for sedation. Best Practice & Research Clinical Anaesthesiology. 2018 Jun 1;32(2):149-64.

Calculators

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농도 희석 계산기

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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