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Cat. No.: HY-186059

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HCN2 modulator-4

HCN2 modulator-4 is a HCN2 ion channel inhibitor. HCN2 modulator-4 inhibits HCN2 ion channel activity. HCN2 modulator-4 can be used for the research of pain, inflammatory pain, neuropathic pain, tinnitus, central nervous system disorders, psychiatric disorders, mood disorders.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 3080809-03-3
화학식: C₂₃H₂₁FN₄O₅
분자량:452.44

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

HCN2 modulator-4 Chemical Structure

CAS No.: 3080809-03-3

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
- In Vitro
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

IC₅₀ & Target

KCNQ2

In Vitro

HCN2 modulator-4 (R-configuration 39; 5 minutes) potently inhibits human HCN2 channels with an IC₅₀ of 10 nM, with reduced activity against human HCN1 and HCN4 channels^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 3080809-03-3
분자량 452.44
화학식 C₂₃H₂₁FN₄O₅
SMILES

O=C(C1=C(OC=C1)C)NC2=NN(C[C@@H](C)OC)C3=NC=C(C4=CC(F)=C(OCO5)C5=C4)C=C23
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Handling Instructions (2659 KB)

References

[1]. Ashok Arasappan, et al. Azaindazole derivatives useful as hcn2 modulators. WO2025072040A1.

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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