JNU-0921
Based on 1 Customer Validation
JNU-0921 is a potent and orally active CD137 agonist. JNU-0921 increases the mRNA expression of IFN-γ and GZMB. JNU-0921 induces luciferase activity with an EC50 value of 64.07 nM.JNU-0921 enhances effector and memory function of cytotoxic CD8+ T cells (CTLs) and alleviates their exhaustion. JNU-0921 also skews polarization of helper T cells toward T helper 1 type and enhances their activity to boost CTL function. JNU-0921 shows anticancer activity.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- Purity: 99.77%
- CAS No.: 3079468-41-7
- 화학식: C19H12N2O3
- 분자량:316.31
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보관:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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용액&용해도
- 순도&문서
- References
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Help & FAQs
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Bioactive Compound Library Max
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MCE Bioactive Compound Library
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Bioactive Compound Library
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Apoptosis Compound Library
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Immunology/Inflammation Compound Library
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Anti-Cancer Compound Library
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Biological Activity
Chemical Information
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CAS No. 3079468-41-7
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Appearance Solid
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분자량 316.31
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화학식 C19H12N2O3
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Color White to off-white
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SMILES
O=C(O)C1=CC(C2=NOC(C3=CC(C=CC=C4)=C4C=C3)=N2)=CC=C1
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
용액&용해도
DMSO : 50 mg/mL (158.07 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
순도&문서
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Data Sheet (272 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.1615 mL | 15.8073 mL | 31.6146 mL | 79.0364 mL |
| 5 mM | 0.6323 mL | 3.1615 mL | 6.3229 mL | 15.8073 mL | |
| 10 mM | 0.3161 mL | 1.5807 mL | 3.1615 mL | 7.9036 mL | |
| 15 mM | 0.2108 mL | 1.0538 mL | 2.1076 mL | 5.2691 mL | |
| 20 mM | 0.1581 mL | 0.7904 mL | 1.5807 mL | 3.9518 mL | |
| 25 mM | 0.1265 mL | 0.6323 mL | 1.2646 mL | 3.1615 mL | |
| 30 mM | 0.1054 mL | 0.5269 mL | 1.0538 mL | 2.6345 mL | |
| 40 mM | 0.0790 mL | 0.3952 mL | 0.7904 mL | 1.9759 mL | |
| 50 mM | 0.0632 mL | 0.3161 mL | 0.6323 mL | 1.5807 mL | |
| 60 mM | 0.0527 mL | 0.2635 mL | 0.5269 mL | 1.3173 mL | |
| 80 mM | 0.0395 mL | 0.1976 mL | 0.3952 mL | 0.9880 mL | |
| 100 mM | 0.0316 mL | 0.1581 mL | 0.3161 mL | 0.7904 mL |
JNU-0921 Related Classifications
HY-161982 Related Classifications
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