(KFF)3K-acpP
(KFF)3K-acpP is an antibacterial agent conjugating of cell penetrating peptide (KFF)3K (HY-P10556) and acpP
peptide nucleic acid. (KFF)3K-acpP binds to the translation start site region of acpP mRNA, sterically blocking ribosome binding and inhibiting translation of the acyl carrier protein. (KFF)3K-acpP induces bacterial envelope stress response pathways, and triggers depletion of outer membrane protein F (ompF) transcript. (KFF)3K-acpP can be used for the research of infections.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
-
보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- 순도&문서
- References
-
Help & FAQs
Biological Activity
peptide nucleic acid. (KFF)3K-acpP binds to the translation start site region of acpP mRNA, sterically blocking ribosome binding and inhibiting translation of the acyl carrier protein. (KFF)3K-acpP induces bacterial envelope stress response pathways, and triggers depletion of outer membrane protein F (ompF) transcript. (KFF)3K-acpP can be used for the research of infections[1].
(KFF) 3K-acpP (1.25 μM; 24 h) inhibits visible growth of UPEC 536 with a MIC of 1.25 μM[1].
(KFF) 3K-acpP (5 μM; 15 min) treatment of UPEC 536 causes a 4.8-fold depletion of acpP mRNA, along with off-target transcript depletion and induction of envelope stress response pathways[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
-
Cell Line:UPEC 536
-
Concentration:5 μM
-
Incubation Time:15 min
-
Result:Caused a 4.8-fold depletion of acpP mRNA.
Chemical Information
-
Sequence
Peptide-PNA:KFFKFFKFFK-CTCATACTCT
-
선적
Room temperature in continental US; may vary elsewhere.
-
보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
(KFF)3K-acpP Related Classifications
HY-P11733 Related Classifications
Powered by Bioz