Laromustine
Based on 1 Customer Validation
Laromustine (VNP40101M) is a compound with antitumor activity. The mechanism of action of Laromustine mainly involves DNA alkylation and DNA repair inhibition. Laromustine can be used for bone marrow transplantation in patients with acute myeloid leukemia and cancer.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- Purity: 99.74%
- CAS No.: 173424-77-6
- 화학식: C6H14ClN3O5S2
- 분자량:307.78
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보관:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
All DNA/RNA Synthesis Isoforms
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Biological Activity
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 173424-77-6
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Appearance Solid
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분자량 307.78
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화학식 C6H14ClN3O5S2
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Color White to off-white
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SMILES
O=C(N(S(=O)(C)=O)N(S(=O)(C)=O)CCCl)NC
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Synonyms
VNP40101M
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
순도&문서
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Data Sheet (267 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Nassar A E F, et al. An in vitro evaluation of the victim and perpetrator potential of the anticancer agent laromustine (VNP40101M), based on reaction phenotyping and inhibition and induction of cytochrome P450 enzymes[J]. Drug metabolism and disposition, 2009, 37(9): 1922-1930. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)