Leukotriene B5
Leukotriene B5 (LTB5) is a leukotriene with diverse biological activities. It is a metabolite of eicosapentaenoic acid formed through the 5-lipoxygenase (5-LO) pathway. LTB5 increases contraction of bullfrog lung strips ex vivo in a concentration-dependent manner. In vivo, LTB5 (100 nM) reduces tumor volume in mice injected with Tm1 murine melanoma cells. LTB5 also elicits chemokinesis and lysosomal enzyme release from polymorphonuclear leukocytes (PMNLs) 20- to 30-fold less, and induces platelet aggregation 8-fold less, potently than LTB4.
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- CAS No.: 80445-66-5
- 화학식: C20H30O4
- 분자량:334.45
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Leukotriene Receptor Isoforms
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Biological Activity
제품 설명
Chemical Information
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CAS No. 80445-66-5
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분자량 334.45
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화학식 C20H30O4
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SMILES
CC/C=C\C/C=C\C[C@@H](O)/C=C/C=C/C=C\[C@@H](O)CCCC(O)=O
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Synonyms
LTB5
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)