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Pexamsiran

Pexamsiran is a siRNA that inhibits plasminogen synthesis, and can be use for the study of hereditary haemorrhagic telangiectasia.

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  • Pexamsiran Chemical Structure
    Pexamsiran Chemical Structure
CAS No.: 3056860-75-1
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  • Pexamsiran Chemical Structure
    Pexamsiran Chemical Structure RNA, (Um-sp-(2′-deoxy-2′-fluoro)A-sp-Gm-Am-Am-(2′-deoxy-2′-fluoro)A-Cm-Um-Cm-Am-Um-Am-Gm-(2′-deoxy-2′-fluoro)C-Gm-(2′-deoxy-2′-fluoro)A-Um-Um-Gm-Cm-Am-sp-Cm-sp-Am), complex with RNA (Um-sp-Gm-sp-Cm-Am-Am-Um-(2′-deoxy-2′-fluoro)C-Gm-(2′-deoxy-2′-fluoro)C-(2′-deoxy-2′-fluoro)U-(2′-deoxy-2′-fluoro)A-Um-Gm-Am-Gm-Um-Um-Um-Cm-Um-Am) 3′-[[(2S,4R)-1-[29-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-14,14-bis[[3-[[3-[[5-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-1-oxopentyl]amino]propyl]amino]-3-oxopropoxy]methyl]-1,12,19,25-tetraoxo-16-oxa-13,20,24-triazanonacos-1-yl]-4-hydroxy-2-pyrrolidinyl]methyl hydrogen phosphate] (1:1)
    1/16
  • RNA, (Um-sp-(2′-deoxy-2′-fluoro)A-sp-Gm-Am-Am-(2′-deoxy-2′-fluoro)A-Cm-Um-Cm-Am-Um-Am-Gm-(2′-deoxy-2′-fluoro)C-Gm-(2′-deoxy-2′-fluoro)A-Um-Um-Gm-Cm-Am-sp-Cm-sp-Am), complex with RNA (Um-sp-Gm-sp-Cm-Am-Am-Um-(2′-deoxy-2′-fluoro)C-Gm-(2′-deoxy-2′-fluoro)C-(2′-deoxy-2′-fluoro)U-(2′-deoxy-2′-fluoro)A-Um-Gm-Am-Gm-Um-Um-Um-Cm-Um-Am) 3′-[[(2S,4R)-1-[29-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-14,14-bis[[3-[[3-[[5-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-1-oxopentyl]amino]propyl]amino]-3-oxopropoxy]methyl]-1,12,19,25-tetraoxo-16-oxa-13,20,24-triazanonacos-1-yl]-4-hydroxy-2-pyrrolidinyl]methyl hydrogen phosphate] (1:1)