Phytosphingosine (Standard)
Phytosphingosine (Standard) is the analytical standard of Phytosphingosine. This product is intended for research and analytical applications. Phytosphingosine is a phospholipid with anti-inflammatory, antibacterial, and anti-cancer activities, which can induce apoptosis. Phytosphingosine is an immune regulator and can be used in the study of inflammatory skin diseases. Phytosphingosine is also an activator of GPR120 with an IC50 value of 33.4 μM and can be used in the study of type II diabetes[1][2][3][4].
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- CAS No.: 554-62-1
- 화학식: C18H39NO3
- 분자량:317.51
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 554-62-1
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분자량 317.51
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화학식 C18H39NO3
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SMILES
CCCCCCCCCCCCCC[C@@H](O)[C@@H](O)[C@@H](N)CO
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Synonyms
4-Hydroxysphinganine (Standard)
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Structure Classification
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Initial Source
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
[1]. 1. Pavicic T, Wollenweber U, Farwick M, et al. Anti‐microbial and‐inflammatory activity and efficacy of phytosphingosine: an in vitro and in vivo study addressing acne vulgaris[J]. International journal of cosmetic science, 2007, 29(3): 181-190. [Content Brief]
[2]. Cai Q, et al. Phytosphingosine inhibits the growth of lung adenocarcinoma cells by inducing G2/M-phase arrest, apoptosis, and mitochondria-dependent pathway cell death in vitro and in vivo. Chem Biol Interact. 2024 Jan 5;387:110795. [Content Brief]
[3]. Glenz R, et al. The major plant sphingolipid long chain base phytosphingosine inhibits growth of bacterial and fungal plant pathogens. Sci Rep. 2022 Jan 20;12(1):1081. [Content Brief]
[4]. Nagasawa T, et al. Phytosphingosine is a novel activator of GPR120. J Biochem. 2018 Jul 1;164(1):27-32. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
- Phytosphingosine (Standard)
- 554-62-1
- 4-Hydroxysphinganine (Standard)
- Reference Standards
- Apoptosis
- Endogenous Metabolite
- Fungal
- Free Fatty Acid Receptor
- Jurkat
- human
- T-cell
- lymphoma
- cell
- apoptosis
- caspase
- A549
- LLC
- BEAS-2B
- C57BL/
- lung cancer
- type II diabetes
- anticancer
- acne
- inflammatory skin disease
- bacteriostasis
- immunomodulator
- Inhibitor
- inhibitor
- inhibit