PRO-F
PRO-F is a photoactivable H2S donor with ROS scavenging ability. PRO-F can be activated by light to produce fluorescent signal, for real-time tracking of released H2S. PRO-F activation doesn’t consume endogenous substances. deliver H2S in an intracellular environment to protect cells from excessive reactive oxygen species (ROS) induced damage. PRO-F shows enhancement on chronic wound healing, researched in diabetic models as well.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- 화학식: C34H29N3O5S
- 분자량:591.68
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
PRO-F (20 μM; 0-500s) can be activated by light activation (365 nm) time-dependently, λex=530 nm, λem=676 nm[1].
PRO-F (20 μM; 5 min, 10 min, 15 min) produces red fluorescent signal in NDF and HaCaT cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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분자량 591.68
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화학식 C34H29N3O5S
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SMILES
CC1(C)CC(/C=C/C2=CC=C(OC(OCC3=CC=C(OCC4=CC=CC=C4[N+]([O-])=O)C=C3)=S)C=C2)=C/C(C1)=C(C#N)/C#N
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)