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Cat. No.: HY-123220

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S 1592

S 1592 is a compound with bronchodilatory and anti-allergic properties. S 1592 significantly suppresses cough caused by respiratory chemical or mechanical stimulation or superior laryngeal nerve electrical stimulation, without affecting gastrointestinal motility, and has low acute toxicity. S 1592 can be used for research on allergic diseases.

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CAS No.: 25552-58-3
화학식: C₂₁H₂₇ClN₂O₃
분자량:390.90

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

S 1592 Chemical Structure

CAS No.: 25552-58-3

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

제품 설명

In Vivo

S 1592 markedly inhibits coughing induced in laboratory animals by chemical or mechanical irritation of respiratory tract or by electrical stimulation of the superior laryngeal nerve^[1].
S 1592 (i.p.) exhibits LD₅₀s of 157 mg/kg and 251 mg/kg in rats and mice, respectively^[1].
S 1592 (i.p.) at LD₅₀ doses causes muscle weakness, irritability, and respiratory distress in mice and rats^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 25552-58-3
분자량 390.90
화학식 C₂₁H₂₇ClN₂O₃
SMILES

O=C(C1=CC=CC=C1O)NCC2(CCN(CC2)CCC3=CC=CC=C3)O.[H]Cl
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. J Duhault, et al. Pharmacological studies of a new antitussive, 1-phenethyl-4-hydroxy-salicylamido-4-methyl-piperidine-hydrochloride (S 1592) (author's transl). Arzneimittelforschung. 1976 Apr;26(4):516-23 [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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