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Cat. No.: HY-118205

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SCH-538415

SCH-538415 is a novel acyl carrier protein synthase inhibitor isolated from an unknown bacterial microorganism. The structural elucidation of compound 1 was completed by analyzing spectral data including UV, MS and 2D-NMR spectra. Compound 1 showed inhibitory activity in the acyl carrier protein synthase (AcpS) test with an IC50 value of 4.19 μM and exhibited antibacterial activity against Staphylococcus aureus in the agar diffusion test.

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CAS No.: 637772-75-9
화학식: C₁₆H₁₄N₂O₄
분자량:298.29

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

SCH-538415 Chemical Structure

CAS No.: 637772-75-9

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- Cellular Effect
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

Cellular Effect

Cell Line	Type	Value	Description	References
BXPC-3	GI₅₀	0.54 μg/mL Compound: 1, SCH-538415	Growth inhibition of human BXPC3 cells Growth inhibition of human BXPC3 cells	[PMID: 16724845]
DU-145	GI₅₀	1 μg/mL Compound: 1, SCH-538415	Growth inhibition of human DU145 cells Growth inhibition of human DU145 cells	[PMID: 16724845]
KM-20L2	GI₅₀	0.32 μg/mL Compound: 1, SCH-538415	Growth inhibition of human KM20L2 cells Growth inhibition of human KM20L2 cells	[PMID: 16724845]
MCF7	GI₅₀	0.49 μg/mL Compound: 1, SCH-538415	Growth inhibition of human MCF7 cells Growth inhibition of human MCF7 cells	[PMID: 16724845]
NCI-H460	GI₅₀	1.2 μg/mL Compound: 1, SCH-538415	Growth inhibition of human NCI-H460 cells Growth inhibition of human NCI-H460 cells	[PMID: 16724845]
P388	GI₅₀	1.4 μg/mL Compound: 1, SCH-538415	Growth inhibition of mouse P388 cells Growth inhibition of mouse P388 cells	[PMID: 16724845]
SF-268	GI₅₀	1.3 μg/mL Compound: 1, SCH-538415	Growth inhibition of human SF268 cells Growth inhibition of human SF268 cells	[PMID: 16724845]

Chemical Information

CAS No. 637772-75-9
분자량 298.29
화학식 C₁₆H₁₄N₂O₄
SMILES

O=C1N(C2=C(C(C)=C1)C(C(C(C)=C3)=C(C2=O)N(C)C3=O)=O)C
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Structure elucidation of Sch 538415, a novel acyl carrier protein synthase inhibitor from a microorganism

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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