WO170
WO170 is a KCNT1 inhibitor that can be used in studies related to diseases associated with KCNT1 dysfunction, such as epilepsy.
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- CAS No.: 3109711-34-1
- 화학식: C25H21N5O
- 분자량:407.47
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
WO170 (I‑1a) is a KCNT1 channel inhibitor, with an IC50 ≤ 250 nM in the FLIPR thallium flux functional inhibition assay performed on HEK293 cells stably expressing human KCNT1[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3109711-34-1
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분자량 407.47
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화학식 C25H21N5O
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SMILES
N#CC1=CC2=C(N[C@H]3CCCC4=C3N=C(O4)C5=CC(C6CC6)=NC=C5)N=CC=C2C=C1
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
- WO170
- 3109711-34-1
- WO 170
- WO-170
- Drug Derivative
- refractory epilepsy
- post-traumatic epilepsy
- focal epilepsy
- infantile epilepsy with migrating focal seizures
- KCNT1
- generalized epilepsy
- sleep-related hypermotor epilepsy
- autosomal dominant nocturnal frontal lobe epilepsy
- epilepsy
- epileptic encephalopathy
- Inhibitor
- inhibitor
- inhibit