L-Ornithine-d6 hydrochloride
Based on 1 Customer Validation
L-Ornithine-d6 hydrochloride is the d6-labeled L-Ornithine hydrochloride (HY-W017018). L-Ornithine hydrochloride is an orally active CaSR and p38 activator. L-Ornithine hydrochloride inhibits ROS and supports urea cycle function. L-Ornithine hydrochloride can be used to study kidney diseases involving proximal tubular cell damage caused by oxidative stress or crystallopathy, as well as research related to anxiety disorders.
For research use only. We do not sell to patients.
- Purity: 99.2%
- CAS No.: 347841-40-1
- Formula: C5H7D6ClN2O2
- Molecular Weight:174.66
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Storage:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Biological Activity
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 347841-40-1
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Unlabeled Cas 3184-13-2
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Appearance Solid
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Molecular Weight 174.66
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Formula C5H7D6ClN2O2
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Color White to off-white
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SMILES
OC([C@@H](N)C([2H])([2H])C([2H])([2H])C([2H])([2H])N)=O.Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
H2O : 50 mg/mL (286.27 mM; ultrasonic and warming and heat to 60°C)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (272 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
[1]. Shin S, et al. l-ornithine activates Ca signaling to exert its protective function on human proximal tubular cells. Cellular signalling. 2020 Mar;67:109484. [Content Brief]
[2]. Demura S, et al. Effect of L-ornithine hydrochloride ingestion on intermittent maximal anaerobic cycle ergometer performance and fatigue recovery after exercise. European journal of applied physiology. 2011 Nov;111(11):2837-43. [Content Brief]
[3]. Kurata K, et al. Orally administered L-ornithine elevates brain L-ornithine levels and has an anxiolytic-like effect in mice[J]. Nutritional Neuroscience, 2011, 14(6): 243-248. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 5.7254 mL | 28.6270 mL | 57.2541 mL | 143.1352 mL |
| 5 mM | 1.1451 mL | 5.7254 mL | 11.4508 mL | 28.6270 mL | |
| 10 mM | 0.5725 mL | 2.8627 mL | 5.7254 mL | 14.3135 mL | |
| 15 mM | 0.3817 mL | 1.9085 mL | 3.8169 mL | 9.5423 mL | |
| 20 mM | 0.2863 mL | 1.4314 mL | 2.8627 mL | 7.1568 mL | |
| 25 mM | 0.2290 mL | 1.1451 mL | 2.2902 mL | 5.7254 mL | |
| 30 mM | 0.1908 mL | 0.9542 mL | 1.9085 mL | 4.7712 mL | |
| 40 mM | 0.1431 mL | 0.7157 mL | 1.4314 mL | 3.5784 mL | |
| 50 mM | 0.1145 mL | 0.5725 mL | 1.1451 mL | 2.8627 mL | |
| 60 mM | 0.0954 mL | 0.4771 mL | 0.9542 mL | 2.3856 mL | |
| 80 mM | 0.0716 mL | 0.3578 mL | 0.7157 mL | 1.7892 mL | |
| 100 mM | 0.0573 mL | 0.2863 mL | 0.5725 mL | 1.4314 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.