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Cat. No.: HY-10843

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LCI765

LCI765 is an orally active and selective PPARδ agonist, with an EC₅₀ of 0.07 nM. LCI765 can be used for the research of diseases related to energy homeostasis such as metabolic syndrome.

For research use only. We do not sell to patients.

CAS No.: 870194-96-0
Formula: C₂₆H₂₀Cl₂N₂O₅
Molecular Weight:511.35

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

LCI765 Chemical Structure

CAS No.: 870194-96-0

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

LCI765 is an orally active and selective PPARδ agonist, with an EC₅₀ of 0.07 nM. LCI765 can be used for the research of diseases related to energy homeostasis such as metabolic syndrome^[1].

IC₅₀ & Target^[1]

PPARγ

0.07 nM (EC₅₀)

All PPAR Isoforms :

Chemical Information

CAS No. 870194-96-0
Molecular Weight 511.35
Formula C₂₆H₂₀Cl₂N₂O₅
SMILES

OC(CC1=CC=CC(C2=NOC(C3=CC=CC=C3)=C2C(NCCOC4=CC=C(Cl)C=C4Cl)=O)=C1)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Epple R, et al. 3,4,5-Trisubstituted isoxazoles as novel PPARdelta agonists. Part 2. Bioorg Med Chem Lett. 2006 Nov 1;16(21):5488-92. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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LCI765

All PPAR Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

LCI765 Related Classifications

HY-10843 Related Classifications