Fatty Amides

OES2-0017 shows potent synergy with polyamines and growth-inhibitory effects at the low micromolar range. OES2-0017 inhibits spermine/spermidine acetyltransferase (SpeG) (IC₅₀: 34.82 μM ) and other polyamine detoxification enzymes in low concentrations, perturbed the bacterial membrane in higher concentrations.

Dymanthine (N,N-Dimethyloctadecan-1-amine) is a broad-spectrum intestinal anthelmintic. Dymanthine is used in research related to various helminth infections (Ascaris lumbricoides, Trichuris trichiura, and Ancylostoma duodenale).

N-18:1 L-Serine sodium is an anandamide.

C18:1 Anandamide is an anandamide.

Ferrioxamine B is a bacterial desferrioxamine siderophore produced by actinomycetes. Ferrioxamine B acts as a ligand for FpvB and FoxA, and is transported into Pseudomonas aeruginosa via the FpvB and FoxA transporters. Ferrioxamine B competitively binds to FpvB, thereby antagonizing the uptake of thiostrepton into Pseudomonas aeruginosa. Ferrioxamine B can provide an iron source to support the growth of Pseudomonas aeruginosa under iron-limiting conditions.

2E,4E-Decadienoylpiperidide (Compound 2) is a cyclic amide compound that can be found in the roots, leaves, and flowers of Achillea ptarmica.

GABA-palmitamide is a GABA-responsive compound. GABA-palmitamide exhibits a dose-dependent bidirectional regulatory effect on the stereotyped behavior induced by Apomorphine (HY-12723): high doses inhibit motor behavior, while low doses enhance stereotyped behaviors in the oral cavity. GABA-palmitamide can be used in research on behavior regulation.

Decanamide is a primary fatty amide.

Arachidonoylmorpholine is a metabolic regulatory molecule related to arachidonic acid metabolism. The level of Arachidonoylmorpholine will increase when the function of the intestinal flora is disrupted. Arachidonoylmorpholine is promising for research of pig gut health, such as post-weaning diarrhea (PWD) in piglets.

Lyso-SM-509, a sphingomyelin, is a biomarker for Niemann-Pick disease Type C.

N-Stearoyltyrosine (N-(1-Oxooctadecyl)-L-tyrosine) is an analog of Anandamide (HY-10863). N-Stearoyltyrosine exhibits neuroprotective efficacy in gerbils ischemia-reperfusion model through protection in the CA1 region of the hippocampus. N-Stearoyltyrosine inhibits the free radicals production and improves antioxidant capacity. N-Stearoyltyrosine inhibits the IR-induced apoptosis.

11(Z),14(Z)-Eicosadienoic acid ethanolamide (Compound 3) is an ethanolamide-conjugated form of 11(Z),14(Z)-Eicosadienoic acid (HY-149589). 11(Z),14(Z)-Eicosadienoic acid ethanolamide inhibits the inactivating transport of an endogenous cannabinoid substance with an IC₅₀ value of 10.6 μM. 11(Z),14(Z)-Eicosadienoic acid ethanolamide can be used for research of neuropsychiatric conditions.

Mead ethanolamide is an endogenous cannabinoid receptor agonist with K_d values of 753 nM and 1810 nM against CB1 and CB2, respectively.

S-2 Methanandamide is a potent CB1 receptor agonist, with IC₅₀ values of 173 nM (with PMSF) and 8216 nM for CB1 and CB2, respectively.

20-HETE Ethanolamide is a metabolite of endocannabinoid Anandamide. 20-HETE Ethanolamide binds to the rat brain cannabinoid CB1 receptor with a K_i of 985 nM.

Docosanoyl Ethanolamide (N-(2-hydroxyethyl)-docosanamide) is an ester product.

9(E)-Octadecenamide (Elaidic acid amide) is an ester product.

Leukotriene B4 ethanolamide (LTB4 ethanolamide) is an antagonist and a partial agonist for Leukotriene B4 (LTB4) receptor 1 (BLTR1). Leukotriene B4 ethanolamide ameliorates the tumor progression, which is only asscociated with inflammation.

Nervonoyl ethanolamide (NEA) is an endogenous cannabinoid that can act as a presynaptic and postsynaptic neuromodulator. Nervonoyl ethanolamide can also be used in the research of inflammation.

PGD2 ethanolamide is the COX-2 dependent metabolite of Anandamide that induces apoptosis in colorectal carcinoma (CRC) cells.