Fatty Amides

N,N-Bis(3-aminopropyl)dodecylamine is a potent fungicidal agent with remarkable activity against Aspergillus niger. N,N-Bis(3-aminopropyl)dodecylamine induces oxidative stress and regulates the activities of multiple antioxidant and mitochondrial enzymes in a concentration‑ and duration‑dependent manner. N,N-Bis(3-aminopropyl)dodecylamine disrupts fungal organelles, remodels mitochondrial morphology and impairs mitochondria‑related cellular functions. N,N-Bis(3-aminopropyl)dodecylamine can be used for the research of fungicidal mechanisms and oxidative stress in Aspergillus niger.

Linoleyl behenate is an ester product.

C18:2 Anandamide phosphate sodium is an anandamide.

N-Stearoyl valine is an N-acyl derivative of valine. N-Stearoyl valine antagonizes intracellular calcium mobilization by binding to the TRPV3 channel as a bioactive endogenous ligand of transient receptor potential (TRP) channels. N-Stearoyl valine participates in physiological processes such as lipid metabolism and cell signal transduction as an endogenous metabolite. N-Stearoyl valine is also a flavor compound. N-Stearoyl valine can be used in research on biomarker detection, animal nutrition and amino acid metabolism, and the development of the food and beverage industry.

Stearoyl glutamic acid (N-Stearoyl-L-glutamic acid) is a saturated aliphatic amide compound and also an additive for lipid cubic phase materials. Stearoyl glutamic acid is used in studies as a surfactant and emulsifier.

3'R-HBHL is a reference compound used for determining the stereochemistry of small bacteriocins.

(E,E)-2,4-Undecadien-8,10-diynoic acid isobutylamide is a natural compound found in Acmella oleracea and is a plant growth inhibitor. (E,E)-2,4-Undecadien-8,10-diynoic acid isobutylamide inhibits the growth of cress roots and shoots and barnyard grass roots.

Agrocybin is an antifungal peptide that exerts antifungal activity against several fungal species but lacks inhibitory activity against bacteria. Agrocybin attenuates the activity of HIV-1 reverse transcriptase.

N-3-Hydroxydecanoyl-L-homoserine lactone is a type of N-acyl-L-homoserine lactone (AHL), which is a class of signaling molecules in bacterial quorum sensing systems, and it has a weak activating effect on AbaR.

Tricosanoyl ethanolamide is a member of endocannabinoids and its structure consists of ethanolamine and tricosanoic acid, which contains 23 carbon atoms. Tricosanoyl ethanolamide can be used for research of diseases related to the endocannabinoid system.

Docosaenoyl ethanolamide (N-(2-Hydroxyethyl)-13Z-docosenamide) is one of a fatty N-acyl ethanolamines. Ethanolamines can be detected at relatively high levels in rat cerebrospinal fluid.

Arachidonamide is substrate of anandamide amidohydrolase.

Anandamide (AEA) is an endogenous cannabinoid that binds to both central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors. The biological actions of AEA are terminated by cellular uptake and hydrolysis of the amide bond by the enzyme fatty acid amide hydrolase. Arachidonoyl-N-methyl amide is an analog of anandamide that binds to the human central cannabinoid (CB1) receptor with a Ki of 60 nM. It inhibits rat glial gap junction cell-cell communication 100% at a concentration of 50 μM.

Stearoyl serotonin is a hybrid molecule patterned after arachidonoyl serotonin. Arachidonoyl serotonin is a dual antagonist of fatty acid amide hydrolase (FAAH) and the transient receptor potential vanilloid-type 1 (TRPV1) channel, reducing both acute and chronic peripheral pain. The effects of replacing the arachidonoyl portion with the saturated 18-carbon stearoyl moiety have not been studied. However, replacement of arachidonate with saturated 11- or 12-carbon fatty acids produces compounds that potently inhibit capsaicin-induced TRPV1 channel activation (IC₅₀=0.76 μM) without blocking FAAH-mediated hydrolysis of arachidonoyl ethanolamine (IC₅₀ > 50 μM).

Lignoceroyl ethanolamide is a member of the family of fatty N-acyl ethanolamines collectively called endocannabinoids. Whereas lignoceric acid has been detected at relatively high levels in rat cerebrospinal fluid, the specific role and relative importance of its ethanolamine metabolite have not been determined.

N-Stearoyldopamine is a lipid molecule. N-Stearoyldopamine forms monolayer, which acts as an adhesion promoter between a substrate and a bulk polymer.

Pentadecanoyl ethanolamide is derivate of endougenous lipid amides, the N-acylethanolamines. Pentadecanoyl ethanolamide exhibits anticonvulsant efficacy in electroshocked mice without significant toxicity.

Commendamide is a GPCR G2A/GPR132 agonist (EC₅₀: 11.8 μM). Commendamide can be used for research of autoimmunity and atherosclerosis.