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Cat. No.: HY-N22000

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N-Stearoyl valine

N-Stearoyl valine is an N-acyl derivative of valine. N-Stearoyl valine antagonizes intracellular calcium mobilization by binding to the TRPV3 channel as a bioactive endogenous ligand of transient receptor potential (TRP) channels. N-Stearoyl valine participates in physiological processes such as lipid metabolism and cell signal transduction as an endogenous metabolite. N-Stearoyl valine is also a flavor compound. N-Stearoyl valine can be used in research on biomarker detection, animal nutrition and amino acid metabolism, and the development of the food and beverage industry.

For research use only. We do not sell to patients.

CAS No.: 14379-32-9
Formula: C₂₃H₄₅NO₃
Molecular Weight:383.61

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

N-Stearoyl valine Chemical Structure

CAS No.: 14379-32-9

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

IC₅₀ & Target

^[2]

TRPV3

All Endogenous Metabolite Isoforms :

All TRP Channel Isoforms :

In Vitro

N-Stearoyl valine is a lipoamino acid derivative (belonging to the class of N-acyl amide compounds) formed by the conjugation of stearic acid and valine via an amide bond^[4].
N-Stearoyl valine antagonizes intracellular calcium mobilization by binding to the TRPV3 channel^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 14379-32-9
Molecular Weight 383.61
Formula C₂₃H₄₅NO₃
SMILES

CCCCCCCCCCCCCCCCCC(N[C@H](C(O)=O)C(C)C)=O
Structure Classification
- Lipids
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Rahim N A, et al. Antioxidant activity, total phenolic and flavonoid content and LC–MS profiling of leaves extracts of Alstonia angustiloba. Separations, 2022, 9(9): 234.

[2]. Gómez E, et al. Non-invasive metabolomics for improved determination of embryonic sex markers in chemically defined culture medium. Journal of chromatography. A. 2016 Nov 25;1474:138-144.

[3]. Zhang X, et al. Valine Supplementation in a Reduced Protein Diet Regulates Growth Performance Partially through Modulation of Plasma Amino Acids Profile, Metabolic Responses, Endocrine, and Neural Factors in Piglets. Journal of agricultural and food chemistry. 2018 Mar 28;66(12):3161-3168.

[4]. Feng Shi, et al. Organic Compounds. US20150072060A1. USPTO. 2015-2-12.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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